Posts

Showing posts from March, 2020

Why does soap work so well on most viruses?

Image
Soap is better if you rub with it for 20 secs Note that the below article is based on @PalliThordarson 's tweets. What Is Virus? Building Blocks Most viruses consist of three key building blocks: RNA The RNA is the viral genetic material -it is very similar to DNA. Proteins The proteins have several roles including breaking into the target cell, assist with virus replication and basically to be a key building block (like a brick in a house) in the whole virus structure. Lipids The lipids then form a coat around the virus, both for protection and to assist with its spread and cellular invasion. The RNA, proteins and lipids self-assemble to form the virus. Critically, there are no strong “covalent” bonds holding these units together.  Instead the viral self-assembly is based on weak “non-covalent” interactions between the proteins, RNA and lipids. Together these act together like a Velcro so it is very hard to break up the self-assembled viral partic...

Precautions You Probably Should Take

Image
The author of this coronavirus precautionary measures is James Robb, MD UC San Diego. It’s a really great read. Subject: What I am doing for the upcoming COVID-19 (coronavirus) pandemic Dear Colleagues, as some of you may recall, when I was a professor of pathology at the University of California San Diego, I was one of the first molecular virologists in the world to work on coronaviruses (the 1970s). I was the first to demonstrate the number of genes the virus contained. Since then, I have kept up with the coronavirus field and its multiple clinical transfers into the human population (e.g., SARS, MERS), from different animal sources. The current projections for its expansion in the US are only probable, due to continued insufficient worldwide data, but it is most likely to be widespread in the US by mid to late March and April. Here is what I have done and the precautions that I take and will take. These are the same precautions I currently use during our influenza seasons, exce...