Immunological Memory — The Source of Protective Immunity from a Subsequent Infection
While many successful vaccines act primarily by generating antibodies , there is also a clear need for vaccines that generate populations of highly-specific T cells , especially against infectious agents that successfully escape antibody responses. [1] Latest Developments Based on a latest research, it stated that: [16] These results provide further evidence that a three-dose vaccine regimen benefits the induction of optimal functional T cell immune memory. Table 1. Vaccines do generate populations of highly-specific T cells (Source @erictopol ) Innate Immune System vs Adaptive Immune System The innate immune system is a conserved defense strategy critical for the initial detection and restriction of pathogens and later activation of the adaptive immune response . Effective activation of innate immunity relies on the recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and RIG...